Abstract

Vitamin D deficiency is increasingly associated with metabolic disorders such as insulin resistance, diabetes, and dyslipidemia. These disorders are very common today due to poor dietary habits and certain metabolic diseases. The aim of the study was to assess the association between vitamin D levels and metabolic indicators, such as, insulin, glycated hemoglobin (HbA1c) and blood lipid values in diabetic and prediabetic patients. Laboratory data were used to conduct a cross-sectional research. Statistical analysis involved analysis of variance (ANOVA) to compare groups and Pearson correlation coefficient to determine relationships between variables. There was a great difference in the levels of vitamin D between the sexes (F = 7.83, p = 0.010). A strong negative correlation was also found between vitamin D and insulin (r = -0.73). Moreover, there was a significant positive correlation between age and glycated hemoglobin (r = 0.74) as well as LDL cholesterol and total cholesterol (r = 0.81). Vitamin D deficiency is strongly associated with insulin resistance and metabolic disorders, which emphasize its possible involvement in metabolic health.