Mechanisms of Development of Multidrug Resistance (MDR) in Intestinal E. coli Bacteria Causing Urinary Tract Infections
Abstract
Background: Urinary tract infections (UTIs) are among the most common bacterial infections worldwide. Studies indicate that E.coli bacteria are responsible for the majority of these infections, especially in women. The danger of these infections lies in their recurrence and rapid progression if there is no response to treatment.
Methods: 30 samples were collected for the period from December 2025 to March 2026,from patients of both sexes and different ages whom suffering from urinary tract infections and cultured using appropriate media such as MacConkey agar and EMB agar, in addition to microscopic and biochemical examinations.
The results: The E. coli bacteria were among the most common pathogens. The colonies appeared pink on MacConkey agar and metallic green sheen on EMB agar. Microscopic examinations showed that they were Gram-negative bacilli, and biochemical tests confirmed their positivity for the catalase test and their negativity for the oxidase test.
The results of antibiotic susceptibility testing of the isolates using Mueller Hinton agar showed high resistance rates were recorded for ceftriaxone and trimethoprim/SXT. While high susceptibility to imipenem and amikacin,. A clear prevalence of multidrug resistance (MDR) was also observed, in addition to co-resistance among several drug classes.
How to Cite This Article
Seenaa J Allawande (2026). Mechanisms of Development of Multidrug Resistance (MDR) in Intestinal E. coli Bacteria Causing Urinary Tract Infections . International Journal of Biological and Biomedical Research (IJBBMR), 2(3), 35-40. DOI: https://doi.org/10.54660/IJBBR.2026.2.3.35-40