Genetic Regulation of Apoptosis in Cancerous vs. Normal Cells
Abstract
Apoptosis, or programmed cell death, is a tightly regulated process essential for maintaining cellular homeostasis. Disruptions in apoptotic pathways contribute to cancer development by allowing uncontrolled cell proliferation. This paper explores the genetic mechanisms regulating apoptosis in normal versus cancerous cells, focusing on key genes such as TP53, *BCL-2*, and CASPASE families. Additionally, we examine how mutations in these genes lead to evasion of apoptosis in cancer and discuss potential therapeutic strategies targeting apoptotic pathways.
How to Cite This Article
Elizabeth M Johnson (2025). Genetic Regulation of Apoptosis in Cancerous vs. Normal Cells . International Journal of Biological and Biomedical Research (IJBBMR), 1(1), 01-02.